STANDARDS SETTING FOR MCQ, OSPE & OSCE - A QUALITY CONTROL MEASURE IN ASSESSMENT

In this post different types of standard setting methods have been described. Among the different types, fixed percentage method, Angoff's method (Angoffing) and Hofstee have been described with their advantages and disadvantages.Commonly used standard setting methods for objective structured clinical examination (OSCE) have also also been described.

PRINCIPLES OF TERATOLOGY AND CRITICAL STAGES OF DEVELOPMENT

This note defines a teratogen and explains the principles governing the capacity of a teratogen to produce teratogenic effect with emphasis on the effect of a teratogen on different developmental stages.

HISTOLOGICAL FEATURES OF SPLEEN



General Structure of spleen
The spleen is the largest accumulation of lymphoid tissue in the body. The spleen is surrounded by a capsule of dense connective tissue from which emerge trabeculae, which divide the parenchyma, or splenic pulp, into incomplete compartments. Large trabeculae originate at the hilum, on the medial surface of the spleen; these trabeculae carry nerves, arteries and veins.

In humans, the connective tissue of the capsule and trabeculae contains only a few smooth muscle cells, contrary to what occurs in several animals (eg, horses, dogs, and cats). 

GROSS ANATOMY OF SPLEEN



Shape of Spleen
The spleen is an ovoid, usually purplish, pulpy, soft, vascular (sinusoidal) mass about the size and shape of one's fist. The spleen is 1 inch thick, 3 inches wide, 5 inches long, and weighs 7 ounces.







HISTOLOGICAL FEATURES OF TONSIL



Tonsils
Tonsils belong to the mucosa associated lymphoid tissue (MALT), but because they are incompletely encapsulated, they are considered organs and will be studied apart from the MALT. The tonsils constitute a lymphoid tissue that lies beneath, and in contact with, the epithelium of the initial portion of the digestive tract. Depending on their location, tonsils in the mouth and pharynx are called palatine, pharyngeal, or lingual.

HISTOLOGICAL FEATURES OF LYMPH NODE



Lymph Nodes
Lymph nodes are distributed throughout the body along the course of the lymphatic vessels. The nodes are found in the axilla and the groin, along the great vessels of the neck, and in large numbers in the thorax and abdomen, especially in mesenteries. Lymph nodes constitute a series of in-line filters that are important in the body's defense against microorganisms and the spread of tumor cells. All this lymph, derived from tissue fluid, is filtered by at least one node before returning to the circulation.

Gross Features of Lymph Nodes
Lymph nodes are elongated or kidney-shaped organs that have a convex surface that is the entrance site of lymphatic vessels and a concave depression, the hilum, through which arteries and nerves enter and veins and lymphatic vessels leave the organ (Figure- 1). A connective tissue capsule surrounds the lymph node, sending trabeculae into its interior.

LYMPHOID TISSUE: A BRIEF OUTLINE



The body has a system of cells—the immune system—has the ability to neutralize or inactivate foreign molecules (such as soluble molecules as well as molecules present in viruses, bacteria, and parasites) and to destroy microorganisms or other cells (such as virus-infected cells, cells of transplanted organs, and cancer cells).

The cells of the immune system have following general characteristics:
1.      They are distributed throughout the body in the blood, lymph, and epithelial and connective tissues;
2.      They are arranged in small spherical nodules called lymphoid nodules found in connective tissues and inside several organs and
3.      They are organized as differently sized organs called lymphoid organs— like the lymph nodes, the spleen, the thymus, and the bone marrow.
a.      Spleen and thymus are called primary or central lymphoid organs.
b.      Lymph nodes, spleen and other lymphoid tissues line tonsil are called secondary or peripheral lymphoid organs.

MUSCLES OF RESPIRATION



Respiration involves Inspiration and Expiration which are accompanied by the alternate increase and decrease of the volume of thoracic cavity. 

Inspiration is an active process and is achieved by increase in all diameters of thoracic cavity. (Thoracic cavity has three diameters – vertical, transverse and anteroposterior.)

The muscles involved in inspiration are:

Diaphragm:
Diaphragm is the primary muscle of inspiration.It increases all the three diameters of thorax.

GROSS ANATOMY AND HISTOLOGICAL FEATURES OF THYROID GLAND



The thyroid is a highly vascular ductless gland found deep in the neck region and overlapped by the anterior neck muscles.
Location of the thyroid gland:
It situated in front and at the sides of trachea opposite 5th, 6th, 7th cervical and 1st thoracic vertebrae in the neck region.

Intrinsic or Deep or Paraspinal Muslces of Back: Brief Outline



What are Paraspinal Muscles or Deep Muscles or Intrinsic Muscles of back?
These are deep or intrinsic back muscles. These muscles form a prominent mass on each side of the spinal column extending from base of the skull to the sacrum. These muscles consists of many separate, overlapping muscles of different lengths, attached to the spinous or transverse processes of different vertebrae. 

Structure and Function of Skin

Structure of Skin



Layers of the skin (from superficial to deep) are:
Epidermis – it is made up of stratified squamous epithelium keratinized
Dermis – it is made up of connective tissue.

Cranial Dura Mater and Dural Venous Sinuses

Objectives:
Describe the features (and reflections/foldings) of cranial dura mater.
Describe the intracranial dural venous sinuses.

The brain is covered from outside inwards by three meningeal layers namely
                  
i)         Dura mater
ii)       Arachnoid mater and
iii)     Pia mater.

Dura Mater:
 It is tough and consists of
outer endosteal/periosteal layer which serves as inner periosteum (covering inside of the bones that form the calvaria of skull) and
inner meningeal layer which is a strong fibrous membrane that is continuous at the foramen magnum with the spinal dura mater covering the spinal cord.

Muscles of the Eye-lid: Actions and Innervations

Objective
Describe the muscles of eye lid, their actions and innervations.

Muscles of eyelid: Their Actions and Innervations
            The muscles of the eyelids are:

Levatorpalpebræsuperioris (LPS)

Orbicularis oculi

Corrugator
 

Extra-ocular Muscles of Eye: their attachment, actions and nerve supply



Objectives:

Describe the attachment of extra-ocular muscles.
Describe the action and nerve supply of extra-ocular muscles.


Extra-ocular muscles of eye
The muscle acting on the eye ball to produce various movements of eye are called extr-aocular muscles which consists of

Four recti
Two oblique muscles
Superior rectus
Superior oblique
Inferior rectus
Inferior oblique
Medial rectus

Lateral rectus